Stain different, tag FAST
The Twinkle Factory is rooted in the wish of Arnaud Gautier, Ludovic Jullien and Franck Perez, three top-notch scientists of ENS-PSL, Sorbonne University, and Institut Curie to help life science researchers accelerate their work. The Twinkle Factory thus distributes reagents for their breakthrough protein fluorescent reporters and molecular glues, FAST and splitFAST (What is it, FAST and splitFAST?), and CATCHFIRE (What is it, CATCHFIRE?).
It all started in 2019 with a three-item-long pricelist for FAST and splitFAST. Along with cofounders’ research, non-permeant fluorogens, a far-red fluorogen, a fluorescence quencher, have added to the list. As a result, sales rapidly expanded worldwide. So far, 300 research teams at universities, life sciences startups, big pharmas, CROs, have implemented FAST and splitFAST in their research. Their key words are metabolic engineering, microbiota, protein-protein interactions, synthetic biology, cell-based assays, sensors… Furthermore, they unveiled the potential of FAST in hypoxic conditions, equipping a vast array of microorganisms.
And in 2023, we have added a whole range of fluorogenic molecular glues for CATCHFIRE.
This is just the beginning! Actinometers, and many other twinkling reagents are indeed joining the pack. Stay tuned!
Our latest post
One more! FAST in Corynebacterium glutamicum
disclosed in Microb. Cell Fact. by KAIST researchers
Our earlier posts
Fluorogenic molecular glues for CATCHFIRE now available
Request your two-for-the-price-of-one bonus!
FAST for multicolor imaging of Pseudomonas aeruginosa
phiLOV2.1 and FAST found to be the best match
FAST biosensors: glutamate, K+, ATP, and more to come
just published in ACS Sensors by Prof. A. Gautier’s team
Click-FAST: FAST and click chemistry for à-la-carte fluorescent reporting
just disclosed by researchers of OHSU School of Dentistry
CATCHFIRE, a brandnew self-reporting protein dimerizer
just published in Nat. Methods by A. Gautier and F. Perez
FAST in anaerobic thermophiles for the first time ever
Towards C1-based biofuels and chemicals! By R. Hocq of TU Wien
FAST nanoprobes for anaerobic tracking of gut microbiota vesicles
disclosed by Shanghai Jiao Tong University in ACS Nano
FAST and splitFAST, greenFAST & redFAST, pFAST in a nutshell
A review of this exciting journey in Account Chemistry Research by inventor Prof. Arnaud Gautier
FAST and splitFAST to the fore at CLOSTRIDIUM XVI
three talks and one poster reviewing FAST of The Twinkle Factory in acetogenic and solventogenic Clostridia
FAST in archaea imaging: towards a new standard
FAST in anaerobic methanogenic archaea FACSing just reported in bioRxiv by N. Adlung of Uni Aalto
Microbiota in vivo imaging with FAST-encoded bacterial probes
Gut and tumor microbiota in vivo imaging disclosed by a team of the Shanghai Jiao Tong University
FAST and splitFAST in Archaea for the first time ever!
FAST and splitFAST in Archaea just disclosed by Kyle Costa’s lab at University of Minnesota
Thanks to the continued support of PSL Université and Région Ile-de-France.