Stain different, tag FAST
Stain Different Tag FAST with The Twinkle Factory! This is how everything got started in 2017 from the wish of Arnaud Gautier, Ludovic Jullien and Franck Perez, three top-notch scientists from ENS-PSL, Sorbonne University, and the Institut Curie to help others accelerate their research.
Seeing cellular mechanisms is the first step towards understanding the inner workings of living systems. But many biological molecules and processes are yet to be unveiled. Our research aims at inventing new ways of observing biomolecules and cellular events via next-generation fluorescent labels in cell-based assays, live cell imaging, cytometry.
The Twinkle Factory’s products are based on the instantaneous formation of a fluorescent molecular assembly between the FAST protein or splitFAST and fluorogenic ligands (Fluorogens). Only the assembly of both the tag and the Fluorogen fluoresce, allowing specific detection by fluorimetry or optical microscopy. We hence provide efficient tools for various applications in biological imaging, from fundamental mechanisms to drug screening.
Our latest post
FAST and splitFAST, greenFAST & redFAST, pFAST in a nutshell
A review of this exciting journey in Account Chemistry Research by inventor Prof. Arnaud Gautier
Our earlier posts
First-ever report of FAST in anaerobic Giardia intestinalis
In BMC Biology by Charles University and Ludwig-Maximilians University researchers
FAST to explore multi-species low-oxygen biofilms
In this npj Biofilms Microbiomes issue, Prof. Henry builds up FAST experience for biofilms studies
Monitoring butanol production with FAST in acetogenic bacteria
FAST in Eubacterium limosum by Prof. Dr. Peter Dürre of Ulm University – Biotechnology for Biofuels
Metabolic engineering in Saccharomyces cerevisiae with FAST
Adding Saccharomyces cerevisiae to the array of FAST and splitFAST applications
What about FAST for anaerobic protozoa fluorescence labeling?
Struggling for florescence labeling of parasitic protozoa? Some food for thought at the onset of a new year
The Twinkle Factory and e-Zyvec partner for FAST plasmid design
Want to try FAST of The Twinkle Factory? Check e-Zyvec, the worldwide expert in FAST vectors, to expedite your research
Congratulations to Tübingen on the IGEM 2020 Gold Medal
Sincerely happy to help iGEM teams inventing new tools for tomorrow’s synthetic biology
frFAST and split-frFAST plasmids now available at Addgene
Want to expedite implementation of frFAST and split-frFAST? Check for plasmids at Addgene
The Twinkle Factory community adds three new countries in Q3
This video tracks The Twinkle Factory expanding fluorogen sales worldwide since early 2019
FAST unveils Listeria intravacuolar proliferation
Decipher Listeria invasion pathways with Prof. Desprat and Dr. Lebreton by means of FAST
The patent application for splitFAST just published by EPO
The EPO has just published the patent application for splitFAST by Prof. Arnaud Gautier and Dr. Alison Tebo
Visualizing bacterial protein export with FAST
Scientific Reports officially announces the union of FAST and Listeria witnessed by Prof. Beloin and Prof. Desprat