Stain different, tag FAST
The Twinkle Factory is rooted in the wish of Arnaud Gautier, Ludovic Jullien and Franck Perez, three top-notch scientists from ENS-PSL, Sorbonne University, and the Institut Curie to help life science researchers accelerate their work. The Twinkle Factory thus distributes reagents for their breakthrough protein fluorescent reporters and molecular glues, FAST and splitFAST (What is it, FAST and splitFAST?), and CATCHFIRE (What is it, CATCHFIRE?).
It all started in 2019 with a three-item-long pricelist for FAST and splitFAST. Along with cofounders’ research, non-permeant fluorogens, a far-red fluorogen, a fluorescence quencher, have added to the list. As a result, sales rapidly expanded worldwide. So far, 300 research teams at universities, life sciences startups, big pharmas, CROs, have implemented FAST and splitFAST in their research. Their key words are metabolic engineering, microbiota, protein-protein interactions, synthetic biology, cell-based assays, sensors… Furthermore, they unveiled the potential of FAST in hypoxic conditions, equipping a vast array of microorganisms.
And in 2023, we have added a whole range of fluorogenic molecular glues for CATCHFIRE.
This is just the beginning! Actinometers, and many other twinkling reagents are indeed joining the pack. Stay tuned!
Our latest post
Our earlier posts
Gut and tumor microbiota in vivo imaging disclosed by a team of the Shanghai Jiao Tong University
FAST and splitFAST in Archaea just disclosed by Kyle Costa’s lab at University of Minnesota
For protein trafficking / excretion studies – After A. Gautier in Nat. Commun. 2021
For your most demanding multi-step multi-color protocols – after Arnaud Gautier in Nat. Commun. 2021
A collaboration of Ulm University and the University of Nottingham published in Applied Microbiology and Biotechnology
Towards #CarbonSmart – by M. Flaiz of Ulm University – in ACS Synth. Biol.
In Nat. Commun., Prof. Arnaud Gautier discloses an improved pFAST and a variety of novel fluorogens
The USPTO has just granted the patent for non-permeant FAST fluorogens by Prof. Arnaud Gautier et al.
In BMC Biology by Charles University and Ludwig-Maximilians University researchers
In this npj Biofilms Microbiomes issue, Prof. Henry builds up FAST experience for biofilms studies
FAST in Eubacterium limosum by Prof. Dr. Peter Dürre of Ulm University – Biotechnology for Biofuels
Adding Saccharomyces cerevisiae to the array of FAST and splitFAST applications