Stain different, tag FAST
Stain Different Tag FAST with The Twinkle Factory! This is how everything got started in 2017 from the wish of Arnaud Gautier, Ludovic Jullien and Franck Perez, three top-notch scientists from ENS-PSL, Sorbonne University, and the Institut Curie to help others accelerate their research.
Seeing cellular mechanisms is the first step towards understanding the inner workings of living systems. But many biological molecules and processes are yet to be unveiled. Our research aims at inventing new ways of observing biomolecules and cellular events via next-generation fluorescent labels in cell-based assays, live cell imaging, cytometry.
The Twinkle Factory’s products are based on the instantaneous formation of a fluorescent molecular assembly between the FAST protein or splitFAST and fluorogenic ligands (Fluorogens). Only the assembly of both the tag and the Fluorogen fluoresce, allowing specific detection by fluorimetry or optical microscopy. We hence provide efficient tools for various applications in biological imaging, from fundamental mechanisms to drug screening.
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The USPTO has just granted the patent for non-permeant FAST fluorogens by Prof. Arnaud Gautier et al.
In BMC Biology by Charles University and Ludwig-Maximilians University researchers
In this npj Biofilms Microbiomes issue, Prof. Henry builds up FAST experience for biofilms studies
FAST in Eubacterium limosum by Prof. Dr. Peter Dürre of Ulm University – Biotechnology for Biofuels
Adding Saccharomyces cerevisiae to the array of FAST and splitFAST applications
Struggling for florescence labeling of parasitic protozoa? Some food for thought at the onset of a new year
Want to try FAST of The Twinkle Factory? Check e-Zyvec, the worldwide expert in FAST vectors, to expedite your research
Sincerely happy to help iGEM teams inventing new tools for tomorrow’s synthetic biology
Want to expedite implementation of frFAST and split-frFAST? Check for plasmids at Addgene
This video tracks The Twinkle Factory expanding fluorogen sales worldwide since early 2019
Decipher Listeria invasion pathways with Prof. Desprat and Dr. Lebreton by means of FAST