Jul 10, 2023 | Anaerobe labeling
FAST in anaerobic thermophiles for the first time ever! TU Wien’s Rémi Hocq et al. have just reported FAST in Thermoanaerobacter kivui in Front. Bioeng. Biotechnol. 2023. Why anaerobic thermophiles? Anaerobic thermophilic bacteria are top-of-the-list candidates...
Oct 24, 2022 | FAST and splitFAST, The Twinkle Factory
FAST and splitFAST, and all variants, and related fluorogens, in this straightforward review authored by inventor Arnaud Gautier published in Acc. Chem. Res. 2022. In this Account, Arnaud Gautier navigates through the FAST journey starting from the princeps paper in...
Feb 21, 2022 | FAST and splitFAST, Fluorogens, The Twinkle Factory
The membrane non-permeant fluorogen TFFox-NP adds to the ever-expanding toolkit of The Twinkle Factory. Indeed, it is coming after the dark chromophore TFDarth just released, and the far-red fluorogen TFPoppy in 2020. TFFox-NP belongs to the group of membrane...
Feb 14, 2022 | FAST and splitFAST, Fluorogens, The Twinkle Factory
The quencher tfDarth adds an exciting novel feature to the ever-expanding toolkit of The Twinkle Factory. tfDarth indeed forms a very tight, non-fluorescent assembly with pFAST. pFAST is the recently disclosed promiscuous variant of the now well-known FAST tag. A...
Jan 31, 2022 | FAST and splitFAST, Fluorogens
Prof. Arnaud Gautier continues leading the development of amazing features of FAST and splitFAST. He, and collaborators, indeed just published in Nat. Commun. 2021 a novel “promiscuous” variant, pFAST. Painting with pFAST is the new motto! As a result...
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