Oct 6, 2026 | FAST and splitFAST
Light can now change the colour of a FAST label, and change it back. A new study shows that FAST tags researchers already use, combined with the right fluorogens, become reversible photoswitches across the whole visible range, and even reversibly photoconvertible...
Sep 30, 2026 | FAST and splitFAST
FLIM-FRET is the most quantitative way to see two proteins come together in a living cell. Its weak spot is the reference: what does “no FRET” look like in that same cell? A new study answers with a FAST acceptor you switch on and off with a fluorogen. The...
Sep 14, 2026 | Catchfire, FAST and splitFAST, The Twinkle Factory
How do you label a protein that you may want to un-label a few seconds later? That question runs through Turning Fluorescence On and Off: Reversible Tags for Live-cell Imaging, an article by Luc Lenglet of The Twinkle Factory, published by Labcompare on 11 September...
Aug 31, 2026 | FAST and splitFAST, Fluorogens
A new fluorogen turns the pFAST tag into a reversible photoswitch, and that opens up imaging you cannot do with an ordinary green label. RSpFAST is not a new tag. It is the pFAST tag paired with a fluorogen that light can flip between two forms. Bound inside pFAST,...
Jun 8, 2026 | FAST and splitFAST
FAST in plants for the first time. Already a workhorse in mammalian cells, yeast and anaerobes, the fluorescence-activating and absorption-shifting tag (FAST) is now disclosed as a versatile protein marker for live plant cell imaging. A collaborative French effort...
Apr 27, 2026 | FAST and splitFAST
Meet LumiFAST: NanoLuc®’s brightness, color-tuned by FAST fluorogens. This new tool emits light without any excitation source, and its emission colour is chosen simply by swapping the fluorogen you add. The work comes from the group of Prof. Arnaud Gautier...
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