Jan 12, 2026 | FAST and splitFAST
pFAST in C. elegans for reversible multicolor labeling. A new microPublication Biology study shows tandem pFAST enables reversible, multicolor chemogenetic fluorescence labeling in dissected C. elegans tissues. Wang, Langevin, Chen and Bai (Fred Hutchinson Cancer...
Feb 10, 2025 | FAST and splitFAST, Fluorogens
Remember frFAST and tfPoppy, the FAST variant and its cognate fluorogenic ligand for protein far-red labelling? You should check this preprint in chemRxiv 2025 by Prof. Péter Kele and team of HUN REN in Budapest. They disclose frFAST and tfPoppy (HPAR-3OM therein)...
Dec 23, 2024 | FAST and splitFAST, Fluorogens, The Twinkle Factory
The Twinkle Factory launches tfCarmine for near-infrared labeling of proteins. The new commercial fluorogen, tfCarmine, forms a bright near-infrared assembly with nirFAST, a variant of the well-known FAST tag. Emitting at 715 nm with a 79-nm Stokes shift, tfCarmine...
Dec 2, 2024 | Catchfire, FAST and splitFAST, Mammals
First disclosure of CATCHFIRE in neurogenesis studies, namely tethering mitochondria and microtubules during the mitosis of neural stemcells. A team led by Evelyne Fischer and Xavier Morin of ENS-PSL (Paris, France) have just disclosed the first application of...
Nov 11, 2024 | Anaerobe labeling, FAST and splitFAST
FAST and splitFAST! Already well described in solventogenic and acetogenic Clostridia strains… Recently disclosed in pathogenic C. difficile… Now in Clostridium perfringens! Thanks to Prof. Stephen Melville and team of Virginia Tech and researchers of...
Oct 21, 2024 | FAST and splitFAST
Monitoring protein tyrosine phosphatases (PTP) activity with FAST and splitFAST. A team led by Amy Barrios of University of Utah have taken the first step toward the development of genetically encodable sensors for PTP activity using FAST. Just published in...
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