Jan 12, 2026 | FAST and splitFAST
pFAST in C. elegans for reversible multicolor labeling. A new microPublication Biology study shows tandem pFAST enables reversible, multicolor chemogenetic fluorescence labeling in dissected C. elegans tissues. Wang, Langevin, Chen and Bai (Fred Hutchinson Cancer...
Aug 25, 2025 | Catchfire, Microbiology
CATCHFIRE in a novel, versatile and high-throughput screening method for protein secretion in Bacillus subtilis. A team of Nanjing Agricultural University hence is the first to disclose CATCHFIRE in bacteria. Initially developed as a self-reporting protein...
Apr 7, 2025 | Catchfire, Fluorogens, The Twinkle Factory
The Twinkle Factory launches the near-infrared dimerizer for CATCHFIRE, match715. Emitting at 715 nm, this fluorescent self-reporting molecular glue completes the CATCHFIRE range at the darker red end. Into chemically induced proximity tools to control protein...
Feb 10, 2025 | FAST and splitFAST, Fluorogens
Remember frFAST and tfPoppy, the FAST variant and its cognate fluorogenic ligand for protein far-red labelling? You should check this preprint in chemRxiv 2025 by Prof. Péter Kele and team of HUN REN in Budapest. They disclose frFAST and tfPoppy (HPAR-3OM therein)...
Jan 13, 2025 | Anaerobe labeling
After reporting FAST in Thermoanaerobacter kivui as a protein fluorescent reporter for the first time ever in 2023, TU Wien’s Rémi Hocq and team have just disclosed Hi-TARGET, a CRISPR type I-B genome-editing tool for the thermophilic acetogen. Building up on...
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