Jul 8, 2024 | FAST and splitFAST
The long-awaited FAST tags for multiplex FLIM (Fluorescence Lifetime Imaging Microscopy) are now here! The team led by Arnaud Gautier of Sorbonne University indeed disclosed FAST-based fluorescence lifetime-modulating tags days ago in Adv. Sci. 2024. Those FAST...
Jul 1, 2024 | FAST and splitFAST
W. Chen and H. Yang of University of Delaware have just introduced a bioPROTAC system for logic-gated, switchable targeted protein degradation. With the help of splitFAST and FAST of The Twinkle Factory. BioPROTACs are heterobifunctional proteins designed for...
Jun 3, 2024 | FAST and splitFAST
Remember the metabolic engineering work in S. cerevisiae of the lab of Claudia Vickers from the University of Queensland? In 2021, they disclosed very elegant strategies, e.g., flux redirecting, metabolic modulation. Selective auxin-mediated degradation of essential...
May 13, 2024 | FAST and splitFAST, Mammals
A team led by Prof. Joris De Wit of KU Leuven has just elucidated the role of a special GPCR in dendritic spine maturation with splitFAST of The Twinkle Factory. Synapses, the junctions connecting neurons into neural circuits, are most diverse, morphologically,...
Mar 4, 2024 | FAST and splitFAST, Mammals
Dr. Joe McKellar et al. from IRIM (Montpellier, France) have just elucidated a modality of interferon-inducible MX1 against Influenza A with FAST of The Twinkle Factory. Myxovirus resistance protein (MX1) is an enzyme of the antiviral response induced by interferons...
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