Apr 7, 2025 | Catchfire, Fluorogens, The Twinkle Factory
The Twinkle Factory launches the near-infrared dimerizer for CATCHFIRE, match715. Emitting at 715 nm, this fluorescent self-reporting molecular glue completes the CATCHFIRE range at the darker red end. Into chemically induced proximity tools to control protein...
Feb 10, 2025 | FAST and splitFAST, Fluorogens
Remember frFAST and tfPoppy, the FAST variant and its cognate fluorogenic ligand for protein far-red labelling? You should check this preprint in chemRxiv 2025 by Prof. Péter Kele and team of HUN REN in Budapest. They disclose frFAST and tfPoppy (HPAR-3OM therein)...
Jan 13, 2025 | Anaerobe labeling
After reporting FAST in Thermoanaerobacter kivui as a protein fluorescent reporter for the first time ever in 2023, TU Wien’s Rémi Hocq and team have just disclosed Hi-TARGET, a CRISPR type I-B genome-editing tool for the thermophilic acetogen. Building up on...
Dec 23, 2024 | FAST and splitFAST, Fluorogens, The Twinkle Factory
The Twinkle Factory launches tfCarmine for near-infrared labeling of proteins. The new commercial fluorogen, tfCarmine, forms a bright near-infrared assembly with nirFAST, a variant of the well-known FAST tag. Emitting at 715 nm with a 79-nm Stokes shift, tfCarmine...
Dec 2, 2024 | Catchfire, FAST and splitFAST, Mammals
First disclosure of CATCHFIRE in neurogenesis studies, namely tethering mitochondria and microtubules during the mitosis of neural stemcells. A team led by Evelyne Fischer and Xavier Morin of ENS-PSL (Paris, France) have just disclosed the first application of...
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