Apr 7, 2025 | Catchfire, Fluorogens, The Twinkle Factory
The Twinkle Factory launches the near-infrared dimerizer for CATCHFIRE, match715. Emitting at 715 nm, this fluorescent self-reporting molecular glue completes the CATCHFIRE range at the darker red end. Into chemically induced proximity tools to control protein...
Feb 10, 2025 | FAST and splitFAST, Fluorogens
Remember frFAST and tfPoppy, the FAST variant and its cognate fluorogenic ligand for protein far-red labelling? You should check this preprint in chemRxiv 2025 by Prof. Péter Kele and team of HUN REN in Budapest. They disclose frFAST and tfPoppy (HPAR-3OM therein)...
Dec 23, 2024 | FAST and splitFAST, Fluorogens, The Twinkle Factory
The Twinkle Factory launches tfCarmine for near-infrared labeling of proteins. The new commercial fluorogen, tfCarmine, forms a bright near-infrared assembly with nirFAST, a variant of the well-known FAST tag. Emitting at 715 nm with a 79-nm Stokes shift, tfCarmine...
Feb 21, 2022 | FAST and splitFAST, Fluorogens, The Twinkle Factory
The membrane non-permeant fluorogen TFFox-NP adds to the ever-expanding toolkit of The Twinkle Factory. Indeed, it is coming after the dark chromophore TFDarth just released, and the far-red fluorogen TFPoppy in 2020. TFFox-NP belongs to the group of membrane...
Feb 14, 2022 | FAST and splitFAST, Fluorogens, The Twinkle Factory
The quencher tfDarth adds an exciting novel feature to the ever-expanding toolkit of The Twinkle Factory. tfDarth indeed forms a very tight, non-fluorescent assembly with pFAST. pFAST is the recently disclosed promiscuous variant of the now well-known FAST tag. A...
Jan 31, 2022 | FAST and splitFAST, Fluorogens
Prof. Arnaud Gautier continues leading the development of amazing features of FAST and splitFAST. He, and collaborators, indeed just published in Nat. Commun. 2021 a novel “promiscuous” variant, pFAST. Painting with pFAST is the new motto! As a result...
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