Jan 1, 2024 | FAST and splitFAST, Mammals
A team led by Paola Pizzo and Riccardo Filadi of the University of Padova has just enabled endoplasmic reticulum-mitochondria junction studies with splitFAST of The Twinkle Factory. The interest in such membrane contact sites (MCSs) between membranous organelles has...
Dec 18, 2023 | FAST and splitFAST
Remember the metabolic engineering work in S. cerevisiae based on auxin-mediated protein degradation of the lab of Claudia Vickers from the University of Queensland, Brisbane? They once disclosed in Nat. Commun. 2021 very elegant strategies for metabolic engineering...
Dec 2, 2023 | FAST and splitFAST, Mammals
Chi-Lun Chang of the St. Jude Children’s Hospital, Alison Tebo of HHMI’s Janelia campus, and team, have just disclosed lipid droplets equipped with splitFAST to enable lipid droplets interactions studies. Contact sites between lipid droplets and other...
Oct 23, 2023 | Anaerobe labeling, FAST and splitFAST
Pseudomonas aeruginosa is joining the family! A team of Ottawa University led by Prof. Campbell-Valois have just reported multicolor imaging of P. aeruginosa with FAST. Check their findings in Front. Microbiol. 2023. P. aeruginosa thrives in the airways of...
Oct 16, 2023 | FAST and splitFAST
Allosteric-like FAST biosensors for glutamate, K+, ATP, just disclosed in ACS Sensors 2023. A work led by Prof. Arnaud Gautier of Sorbonne University, and a co-founder of The Twinkle Factory. Inspired by allosteric proteins, they designed fluorescent sensors...
Oct 2, 2023 | FAST and splitFAST
Click-FAST: FAST and click chemistry combined together for à-la-carte fluorescent reporting! OHSU’s David M. Anderson et al. have just disclosed alkyn-equipped fluorogens, empowering FAST with click chemistry, in bioRxiv 2023. While FAST is a rapidly developing...
Recent Comments