Jul 1, 2024 | FAST and splitFAST
W. Chen and H. Yang of University of Delaware have just introduced a bioPROTAC system for logic-gated, switchable targeted protein degradation. With the help of splitFAST and FAST of The Twinkle Factory. BioPROTACs are heterobifunctional proteins designed for...
May 13, 2024 | FAST and splitFAST, Mammals
A team led by Prof. Joris De Wit of KU Leuven has just elucidated the role of a special GPCR in dendritic spine maturation with splitFAST of The Twinkle Factory. Synapses, the junctions connecting neurons into neural circuits, are most diverse, morphologically,...
Feb 5, 2024 | FAST and splitFAST
splitFAST2 is the next-gen complementation system just published in ACS Chem. Biol. 2024 by Prof. Gautier’s team. Remember! In 2019, they introduced splitFAST, a breakthrough complementation reporter for protein−protein interaction (PPIs) based on the...
Jan 1, 2024 | FAST and splitFAST, Mammals
A team led by Paola Pizzo and Riccardo Filadi of the University of Padova has just enabled endoplasmic reticulum-mitochondria junction studies with splitFAST of The Twinkle Factory. The interest in such membrane contact sites (MCSs) between membranous organelles has...
Dec 2, 2023 | FAST and splitFAST, Mammals
Chi-Lun Chang of the St. Jude Children’s Hospital, Alison Tebo of HHMI’s Janelia campus, and team, have just disclosed lipid droplets equipped with splitFAST to enable lipid droplets interactions studies. Contact sites between lipid droplets and other...
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