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FAST biosensors: glutamate, K+, ATP, and more to come

Oct 16, 2023 | FAST and splitFAST

Allosteric-like FAST biosensors for glutamate, K+, ATP, just disclosed in ACS Sensors 2023.  A work led by Prof. Arnaud Gautier of Sorbonne University, and a co-founder of The Twinkle Factory. Inspired by allosteric proteins, they designed fluorescent sensors...

FAST and splitFAST, greenFAST & redFAST, pFAST in a nutshell

Oct 24, 2022 | FAST and splitFAST, The Twinkle Factory

FAST and splitFAST, and all variants, and related fluorogens, in this straightforward review authored by inventor Arnaud Gautier published in Acc. Chem. Res. 2022. In this Account, Arnaud Gautier navigates through the FAST journey starting from the princeps paper in...

FAST and splitFAST in Archaea for the first time ever!

Jun 13, 2022 | Anaerobe labeling, FAST and splitFAST

FAST and splitFAST in Archaea!  J. Bacteriol. 2022 just reports a team of the University of Minnesota implementing those in Methanococcus maripaludis.  Furthering bacteria and eukaryots, this step opens a brand new domain for The Twinkle Factory. Terry Papoutsakis of...

What about FAST for anaerobic protozoa fluorescence labeling?

Jan 4, 2021 | Anaerobe labeling, FAST and splitFAST

The WHO currently recognizes diarrhoeal diseases as a most significant cause of death in children globally.  Protozoan parasites such as Giardia and Entamoeba are common etiological agents.  They both thrive in the oxygen-deprived environment of the human gut. ...

The Twinkle Factory community adds three new countries in Q3

Oct 26, 2020 | FAST and splitFAST, The Twinkle Factory

https://www.the-twinkle-factory.com/wp-content/uploads/2020/10/Video-The-Twinkle-Factory-community.mp4 The Twinkle Factory community continues expanding. “For the third quarter 2020, The Twinkle Factory community is proud to welcome teams from three new...
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Recent Posts

  • match715, a near-infrared dimerizer for CATCHFIRE, now available
  • Far-red live-cell STED super-resolution microscopy with frFAST and tfPoppy
  • FAST in Thermoanaerobacter kivui – continued
  • The Twinkle Factory launches tfCarmine for near-infrared
  • First disclosure of CATCHFIRE in neurogenesis studies

Recent Comments

  • match715, a near-infrared dimerizer for CATCHFIRE, now available on CATCHFIRE, a brandnew self-reporting protein dimerizer
  • frFAST for far-red labeling disclosed by Prof. Arnaud Gautier on The Twinkle Factory launches tfPoppy for far-red labeling
  • FAST in Thermoanaerobacter kivui - continued on Painting with pFAST, a FAST variant, for advanced imaging
  • Secretory system of Clostridium perfringens with FAST on Visualizing bacterial protein export with FAST
  • FAST in Saccharomyces cerevisiae, a routine technique! on Metabolic engineering in S. cerevisiae with FAST – Cont’d

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