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The Twinkle Factory launches the quencher tfDarth

Feb 14, 2022 | FAST and splitFAST, Fluorogens, The Twinkle Factory

The quencher tfDarth adds an exciting novel feature to the ever-expanding toolkit of The Twinkle Factory. tfDarth indeed forms a very tight, non-fluorescent assembly with pFAST.  pFAST is the recently disclosed promiscuous variant of the now well-known FAST tag.  A...

US patent for non-permeant FAST fluorogens just granted

Oct 18, 2021 | Fluorogens, The Twinkle Factory

The patent US 11,162,951 – Membrane-impermeant fluorogenic chromophores for non-permeant FAST fluorogens was just granted by the USPTO.  The inventors, Arnaud Gautier, Ludovic Jullien, Chenge Li, and Franck Perez, indeed developed very special fluorogens for...

The Twinkle Factory and e-Zyvec partner for FAST plasmid design

Dec 14, 2020 | FAST and splitFAST, The Twinkle Factory

The Twinkle Factory and e-Zyvec are partnering to offer tailor-made FAST plasmid design. & e-Zyvec now offers FAST sequences as standard building blocks in their vector engine, D-Zyvec.  FAST is a genetically encoded breakthrough fluorescence reporting system for...

Congratulations to Tübingen on the IGEM 2020 Gold Medal

Nov 23, 2020 | FAST and splitFAST, The Twinkle Factory

The Twinkle Factory is happy to congratulate the students of Tübingen on their iGEM Gold Medal last week.  And proud that their PacMn project implements FAST tag in a manganese biosensor in E. coli.  PacMn indeed stands for Phytochelatin-actuated complexation of...

frFAST and split-frFAST plasmids now available at Addgene

Nov 9, 2020 | FAST and splitFAST, The Twinkle Factory

frFAST plasmids are now available from Arnaud Gautier Lab Plasmids at Addgene repository. Prof. Arnaud Gautier has recently disclosed frFAST and split-frFAST, variants of FAST and splitFAST, in Angew. Chem. Int. Ed. 2020.  frFAST, combined with the fluorogen HPAR-3OM...

The Twinkle Factory community adds three new countries in Q3

Oct 26, 2020 | FAST and splitFAST, The Twinkle Factory

https://www.the-twinkle-factory.com/wp-content/uploads/2020/10/Video-The-Twinkle-Factory-community.mp4 The Twinkle Factory community continues expanding. “For the third quarter 2020, The Twinkle Factory community is proud to welcome teams from three new...
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Recent Posts

  • match715, a near-infrared dimerizer for CATCHFIRE, now available
  • Far-red live-cell STED super-resolution microscopy with frFAST and tfPoppy
  • FAST in Thermoanaerobacter kivui – continued
  • The Twinkle Factory launches tfCarmine for near-infrared
  • First disclosure of CATCHFIRE in neurogenesis studies

Recent Comments

  • match715, a near-infrared dimerizer for CATCHFIRE, now available on CATCHFIRE, a brandnew self-reporting protein dimerizer
  • frFAST for far-red labeling disclosed by Prof. Arnaud Gautier on The Twinkle Factory launches tfPoppy for far-red labeling
  • FAST in Thermoanaerobacter kivui - continued on Painting with pFAST, a FAST variant, for advanced imaging
  • Secretory system of Clostridium perfringens with FAST on Visualizing bacterial protein export with FAST
  • FAST in Saccharomyces cerevisiae, a routine technique! on Metabolic engineering in S. cerevisiae with FAST – Cont’d

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