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The Twinkle Factory launches the non-permeant fluorogen tfFox-NP

Feb 21, 2022 | FAST and splitFAST, Fluorogens, The Twinkle Factory

The membrane non-permeant fluorogen TFFox-NP adds to the ever-expanding toolkit of The Twinkle Factory.  Indeed, it is coming after the dark chromophore TFDarth just released, and the far-red fluorogen TFPoppy in 2020. TFFox-NP belongs to the group of membrane...

US patent for non-permeant FAST fluorogens just granted

Oct 18, 2021 | Fluorogens, The Twinkle Factory

The patent US 11,162,951 – Membrane-impermeant fluorogenic chromophores for non-permeant FAST fluorogens was just granted by the USPTO.  The inventors, Arnaud Gautier, Ludovic Jullien, Chenge Li, and Franck Perez, indeed developed very special fluorogens for...

The Twinkle Factory and e-Zyvec partner for FAST plasmid design

Dec 14, 2020 | FAST and splitFAST, The Twinkle Factory

The Twinkle Factory and e-Zyvec are partnering to offer tailor-made FAST plasmid design. & e-Zyvec now offers FAST sequences as standard building blocks in their vector engine, D-Zyvec.  FAST is a genetically encoded breakthrough fluorescence reporting system for...

The Twinkle Factory community adds three new countries in Q3

Oct 26, 2020 | FAST and splitFAST, The Twinkle Factory

https://www.the-twinkle-factory.com/wp-content/uploads/2020/10/Video-The-Twinkle-Factory-community.mp4 The Twinkle Factory community continues expanding. “For the third quarter 2020, The Twinkle Factory community is proud to welcome teams from three new...

splitFAST patent application just published by EPO

Oct 12, 2020 | FAST and splitFAST, The Twinkle Factory

The EPO has just published the splitFAST patent application.  The inventors, Prof. Arnaud Gautier and Dr. Alison Tebo, indeed leveled up FAST into splitFAST.  splitFAST is a fluorescence complementation system for visualizing protein-protein interactions in living...
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Recent Posts

  • splitFAST times ER-mitochondria contacts in liver disease
  • Photoconvertible FAST: a label whose colour you switch with light
  • FLIM-FRET with a built-in reference: a FAST acceptor you switch on with a fluorogen
  • Turning fluorescence on and off: our Labcompare article on reversible tags
  • RSpFAST: a FAST tag you can switch with light

Recent Comments

  • match715, a near-infrared dimerizer for CATCHFIRE, now available on CATCHFIRE, a brandnew self-reporting protein dimerizer
  • frFAST for far-red labeling disclosed by Prof. Arnaud Gautier on The Twinkle Factory launches tfPoppy for far-red labeling
  • FAST in Thermoanaerobacter kivui - continued on Painting with pFAST, a FAST variant, for advanced imaging
  • Secretory system of Clostridium perfringens with FAST on Visualizing bacterial protein export with FAST
  • FAST in Saccharomyces cerevisiae, a routine technique! on Metabolic engineering in S. cerevisiae with FAST – Cont’d

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The Twinkle Factory

French biotech supplying fluorogens for the FAST & splitFAST protein tags and fluorogenic molecular glues for CATCHFIRE, chemogenetic reagents for reversible fluorescent labelling and live-cell & in vivo imaging.

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